III · Audience Question 1 Severe Falciparum Malaria04 / 18
Immediate priorities?
01
ABCDE
Simultaneous assessment and resuscitation
02
Sepsis pathway
Activate immediately — don't wait
03
Travel history
Geography is the key diagnostic clue
04
Blood cultures
Before antibiotics
05
Thick + thin films
Request immediately — gold standard
06
Malaria RDT
Rapid antigen test
07
Lactate · ABG · Glucose
Severity markers
08
Early ICU referral
Do not delay escalation
09
Isolation
Consider VHF — Uganda exposure
Differential — febrile returned traveller
P. falciparum malaria
Uganda + no prophylaxis — most likely
Viral haemorrhagic fever
Ebola / Marburg — isolate until excluded
Dengue
NS1 antigen · rash · thrombocytopenia
Typhoid
Rose spots · relative bradycardia
Leptospirosis
Water exposure · uveitis · Weil's
Rickettsiosis
Eschar · tick exposure · serology
Bacterial meningitis
CSF · neck stiffness · photophobia
Acute HIV seroconversion
Lymphadenopathy · screen serology
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